TRRAP 抗体 (AA 3401-3600)
Quick Overview for TRRAP 抗体 (AA 3401-3600) (ABIN1714098)
抗原
See all TRRAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3401-3600
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交叉反应
- 人, 大鼠, 非洲爪蟾
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预测反应
- Mouse,Dog,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TRRAP
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亚型
- IgG
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anti-Transformation/transcription Domain-Associated Protein (TRRAP) (AA 3015-3049), (C-Term) antibody
TRRAP 适用: 人 WB, IF 宿主: 兔 Polyclonal RB51386 unconjugated
anti-Transformation/transcription Domain-Associated Protein (TRRAP) (AA 1703-1737), (C-Term) antibodyTRRAP 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51498 unconjugated
anti-Transformation/transcription Domain-Associated Protein (TRRAP) (AA 3534-3770) antibodyTRRAP 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))
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别名
- TRRAP
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背景
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Synonyms: 350/400 kDa PCAF associated factor, FLJ10671, PAF 350/400, PAF 400, PAF350/400, PAF400, STAF 40, STAF40, TR AP, Tra 1, Tra1, Tra1 homolog, Transactivation / transformation domain associated protein, Transactivation/transformation domain associated protein, Transformation/transcription domain associated protein, TRAP, TRRAP_HUMAN.
Background: The transcription factors c-Myc and E2F are involved in regulating cell cycle progression. Overexpression of c-Myc in certain cell types induces noncycling cells to enter the cell cycle via a mechanism involving E2F-1 (1). E2F-1 is thought to regulate c-Myc expression via interactions with the retinoblastoma protein (2). TRRAP (for transformation/transcription domain-associated protein) interacts specifically with both c-Myc and E2F-1. Expression of trans-activated mutant TRRAP inhibits the oncogenic transformation of both c-Myc and E2F-1, suggesting that TRRAP is required for these oncogenic transcription factor pathways (3). TRRAP shares homology with the ATM/PI 3-kinase family, and it is highly conserved in evolution (4,5).
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基因ID
- 8295
抗原
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