电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

HDAC7 抗体 (pSer486)

This anti-HDAC7 antibody is a 兔 多克隆 antibody detecting HDAC7 in WB, ELISA, IHC (p), IF (cc), IF (p), ICC 和 IHC (fro). Suitable for 人.
产品编号 ABIN1714079
发货至: 中国

Quick Overview for HDAC7 抗体 (pSer486) (ABIN1714079)

抗原

See all HDAC7 抗体
HDAC7 (Histone Deacetylase 7 (HDAC7))

适用

  • 99
  • 67
  • 55
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1

宿主

  • 108
  • 6

克隆类型

  • 100
  • 14
多克隆

标记

  • 53
  • 8
  • 8
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This HDAC7 antibody is un-conjugated

应用范围

  • 75
  • 44
  • 21
  • 14
  • 13
  • 13
  • 8
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 13
    • 13
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer486

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser632

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    HDAC7 (Histone Deacetylase 7 (HDAC7))

    别名

    HDAC7

    背景

    Synonyms: HDAC7 phospho S486, HDAC7 phospho Ser486, p-HDAC7 Ser486, HD 7a, HD7a, HDAC 7, HDAC 7A, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, DKFZP586J0917, OTTHUMP00000202813, OTTHUMP00000202814, FLJ99588, HDAC7_HUMAN.

    Background: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.

    基因ID

    51564

    途径

    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
You are here:
Chat with us!