FAM20C 抗体 (AA 351-450)
Quick Overview for FAM20C 抗体 (AA 351-450) (ABIN1714051)
抗原
See all FAM20C 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 351-450
-
交叉反应
- 大鼠
-
预测反应
- Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Monkey
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human FAM20C
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))
-
别名
- FAM20C
-
背景
-
Synonyms: C76981, Dentin matrix protein 4, DKFZp547C074, DMP-4, DMP4, DMP4_HUMAN, Extracellular serine/threonine protein kinase Fam20C, Fam20C, Family with sequence similarity 20 member C, GEF CK, Golgi enriched fraction casein kinase, Protein FAM20C, RNS antibod.
Background: The FAM20 proteins are a family of secreted proteins that regulate differentiation and function of hematopoietic and other tissues. FAM20C, also known as DMP4 (Dentin matrix protein 4), is a 570 amino acid secreted protein that binds calcium and may play a role in dentin mineralization. Defects in the gene encoding FAM20C are the cause of Raine syndrome (Lethal osteosclerotic bone dysplasia), an autosomal recessive osteosclerotic bone dysplasia, that is characterized by generalized osteosclerosis, microencephaly and craniofacial dysplasia. Usually, affected individuals survive only days or weeks. The mutations of the FAM20C gene include four nonsynomous base changes and four splice-site changes that have a detrimental affect on splicing.
-
基因ID
- 56975
-
UniProt
- Q8IXL6
抗原
-