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CSTF3 抗体 (AA 151-250)

This anti-CSTF3 antibody is a 兔 多克隆 antibody detecting CSTF3 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 和 ICC. Suitable for 小鼠.
产品编号 ABIN1714046
发货至: 中国

Quick Overview for CSTF3 抗体 (AA 151-250) (ABIN1714046)

抗原

See all CSTF3 抗体
CSTF3 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 3, 77kDa (CSTF3))

适用

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小鼠

宿主

  • 45
  • 2
  • 1

克隆类型

  • 47
  • 1
多克隆

标记

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This CSTF3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
  • 抗原表位

    • 14
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    AA 151-250

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CSTF3/CSTF77

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    CSTF3 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 3, 77kDa (CSTF3))

    别名

    CSTF3/CSTF77

    背景

    Synonyms: CF 1 77 kDa subunit, Cleavage stimulation factor 77 kDa subunit, Cleavage stimulation factor subunit 3, Cleavage stimulation factor subunit 3 isoform 1, CSTF 3, CSTF 77, CSTF 77 kDa subunit, CSTF77, MGC117398, MGC43001, MGC75122, CSTF3_HUMAN.

    Background: Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. Heterotrimeric CstF recognizes GU- and U-rich sequences located downstream of the polyadenylation site on RNA. CstF-77 (cleavage stimulation factor, 77 kDa subunit), also known as CstF3, is one of the three subunits comprising CstF. It can exist as a homodimer and functions as the bridge, directly interacting with the other two CstF subunits, namely CstF-64 and CstF-50. CstF-77 is highly conserved among eukaryotes. It contains an Alpha-helical structure with 11 HAT (Half-a-TPR-containing) repeats and is essential for CstF assembly. In addition, CstF-77 is capable of interacting with CPSF1 and FCP1, other factors involved in polyadenylation.

    基因ID

    1479
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