FBXO45 抗体 (AA 110-210)
Quick Overview for FBXO45 抗体 (AA 110-210) (ABIN1714025)
抗原
See all FBXO45 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-210
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Sheep,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FBXO45
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亚型
- IgG
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anti-F-Box Protein 45 (FBXO45) antibody
FBXO45 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 45 (FBXO45) (AA 83-115) antibodyFBXO45 适用: 人 WB 宿主: 兔 Polyclonal RB53750 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FBXO45 (F-Box Protein 45 (FBXO45))
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别名
- FBXO45
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背景
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Synonyms: F box protein 45, F-box only protein 45, F-box/SPRY domain-containing protein 1, FBSP1_HUMAN, FBX45, fbxo45, hFbxo45.
Background: Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IB- and -catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.
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基因ID
- 200933
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UniProt
- P0C2W1
抗原
-
