FAF2 抗体 (AA 81-180)
Quick Overview for FAF2 抗体 (AA 81-180) (ABIN1713972)
抗原
See all FAF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-180
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Sheep,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ETEA
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FAF2 (Fas Associated Factor Family Member 2 (FAF2))
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别名
- ETEA
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背景
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Synonyms: AI462440, expressed in T cells and eosinophils in atopic dermatitis, faf2, FAF2_HUMAN, Fas associated factor family member 2, FAS-associated factor 2, KIAA0887, Protein ETEA, Protein expressed in T cells and eosinophils in atopic dermatitis, Protein expressed in T-cells and eosinophils in atopic dermatitis, UBX domain containing 8, UBX domain protein 3B, UBX domain-containing protein 3B, UBX domain-containing protein 8, UBXD8, UBXN3B.
Background: ETEA is a 445-amino acid protein associated with atopic dermatitis (AD), a chronic noncontagious relapsing inflammatory skin disease characterized by eczematous skin lesions and also referred to as eczematous dermatitis. Other atopic diseases such as hay fever, asthma and conjunctivitis often occur along with AD. ETEA shows higher expression in T cells and eosinophils of patients with AD than in T cells and eosinophils of unaffected individuals. T cells are influential in the regulation of the inflammatory process of this disease. The persistence of jAD is attributed to dysregulated apoptosis in T cells, eosinophils, and keratinocytes. ETEA may be involved in the resistance to apoptosis in T cells and eosinophils of AD patients.
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基因ID
- 23197
抗原
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