PRAM1 抗体 (AA 551-650)
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北京 101111
Quick Overview for PRAM1 抗体 (AA 551-650) (ABIN1713884)
抗原
See all PRAM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 551-650
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PRAM1
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亚型
- IgG
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anti-PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (AA 1-670) antibody
PRAM1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (AA 587-618) antibodyPRAM1 适用: 人 WB 宿主: 兔 Polyclonal RB54864 unconjugated
anti-PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (C-Term) antibodyVerified PRAM1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
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别名
- PRAM1
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背景
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Synonyms: PML RAR, PML RARA regulated adaptor molecule 1, PML RARA target gene encoding an Adaptor Molecule 1, PML-RARA-regulated adapter molecule 1, PRAM 1, PRAM, PRAM-1, PRAM_HUMAN, PRAM1.
Background: Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells. The retinoic acid-induced gene, PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis. PRAM-1 expression is hindered by expression of PML-RAR-a. The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs. PRAM-1 demonstrates expression in hematopoietic tissues and lung.
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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