CPA3 抗体 (AA 101-200)
Quick Overview for CPA3 抗体 (AA 101-200) (ABIN1713752)
抗原
See all CPA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 101-200
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交叉反应
 - 大鼠
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预测反应
 - Human,Mouse
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human CPA3/MC-CPA
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亚型
 - IgG
 
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应用备注
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                        WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
 - 12 months
 
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                                            : "Identification of biomarkers of brown adipose tissue aging highlights the role of dysfunctional energy and nucleotide metabolism pathways."    in: Scientific reports, Vol. 11, Issue 1, pp. 19928, (2021)         (PubMed).        
 
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                                            : "Identification of biomarkers of brown adipose tissue aging highlights the role of dysfunctional energy and nucleotide metabolism pathways."    in: Scientific reports, Vol. 11, Issue 1, pp. 19928, (2021)         (PubMed).        
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- CPA3 (Carboxypeptidase A3 (Mast Cell) (CPA3))
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别名
 - CPA3/MC-CPA
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背景
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Synonyms: carboxypeptidase A, Carboxypeptidase A3, carboxypeptidase A3 mast cell, CBPA3_HUMAN, Cpa3, Mast cell carboxypeptidase A, mast cell carboxypeptidase A3, MC CPA, MC-CPA.
Background: Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.
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基因ID
 - 1359
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途径
 - Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
 
抗原
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