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ARHGAP15 抗体 (AA 201-300)

This 兔 多克隆 anti-ARHGAP15 antibody specifically detects ARHGAP15 in ELISA, WB, ICC, IHC (p), IF (cc), IF (p) 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN1713703
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ARHGAP15 抗体 (AA 201-300) (ABIN1713703)

抗原

See all ARHGAP15 抗体
ARHGAP15 (rho GTPase Activating Protein 15 (ARHGAP15))

适用

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宿主

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克隆类型

  • 21
多克隆

标记

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This ARHGAP15 antibody is un-conjugated

应用范围

ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 201-300

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ARHGAP15

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ARHGAP15 (rho GTPase Activating Protein 15 (ARHGAP15))

    别名

    ARHGAP15

    背景

    Synonyms: ArhGAP15, BM046, Rho GTPase activating protein 15, Rho type GTPase activating protein 15, RHG15_HUMAN.

    Background: Rho GTPases, which play fundamental roles in numerous cellular processes, are initiated by external stimuli that signal though G-protein coupled receptors. ARHGEF15 (Rho guanine nucleotide exchange factor (GEF) 15), also known as ARGEF15 or Vsm-RhoGEF, is a 841 amino acid protein expressed in the vascular smooth muscle of coronary artery. ARHGEF15 functions as a specific guanine nucleotide exchange factor for RhoA and interacts with ephrin-A4 in vascular smooth muscle cells. Containing one DH (DBL-homology) domain, ARHGEF15 is phosphorylated on tyrosine residues upon ephrin-A1 stimulation. The DH domain consists of a region of about 150 amino acids that induces Rho family GTPases to release GDP. This effectively activates the Rho GTPase by allowing GTP binding. ARHGEF15 is encoded by a gene located on human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.

    基因ID

    55843
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