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ADH5 抗体 (AA 301-374)

This anti-ADH5 antibody is a 兔 多克隆 antibody detecting ADH5 in ELISA, FACS, IF (cc), IF (p), IHC (p), ICC 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN1713695
发货至: 中国

Quick Overview for ADH5 抗体 (AA 301-374) (ABIN1713695)

抗原

See all ADH5 抗体
ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

适用

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小鼠

宿主

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克隆类型

  • 63
  • 3
多克隆

标记

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This ADH5 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
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    AA 301-374

    交叉反应

    小鼠

    预测反应

    Human,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ADH5

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

    别名

    ADH5

    背景

    Synonyms: ADH 3, ADH5, ADHX, ADHX_HUMAN, Alcohol dehydrogenase class III chi polypeptide, alcohol dehydrogenase 5 class III chi polypeptide, Alcohol dehydrogenase 5, Alcohol dehydrogenase class 3, Alcohol dehydrogenase class chi chain, Alcohol dehydrogenase class III, Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, class III alcohol dehydrogenase 5 chi subunit, FALDH, FDH, formaldehyde dehydrogenase, Glutathione dependent formaldehyde dehydrogenase, Glutathione-dependent formaldehyde dehydrogenase, GSH-FDH, hydroxymethyllutathione dehydrogenase, S-hydroxymethylglutathione dehydrogenase.

    Background: The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.

    基因ID

    128

    UniProt

    P11766
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