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ACTH 抗体 (pSer168)

This anti-ACTH antibody is a 兔 多克隆 antibody detecting ACTH in ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 和 ICC. Suitable for 人 和 大鼠.
产品编号 ABIN1713643
发货至: 中国

Quick Overview for ACTH 抗体 (pSer168) (ABIN1713643)

抗原

See all ACTH 抗体
ACTH (Adrenocorticotropic hormone (ACTH))

适用

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  • 1
人, 大鼠

宿主

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  • 1

克隆类型

  • 136
  • 59
多克隆

标记

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This ACTH antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
  • 抗原表位

    • 49
    • 43
    • 36
    • 15
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    • 9
    • 7
    • 3
    • 2
    • 2
    pSer168

    交叉反应

    人, 大鼠

    预测反应

    Dog

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human ACTH around the phosphorylation site of Ser168

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ACTH (Adrenocorticotropic hormone (ACTH))

    别名

    ACTH

    背景

    Synonyms: ACTH phospho S168, p-ACTH phospho S168, ACTH, Adrenocorticotropic hormone, Adrenocorticotropin, Alpha melanocyte stimulating hormone, alpha-MSH, alphaMSH, Beta LPH, Beta melanocyte stimulating hormone, Beta-endorphin, beta-MSH, CLIP, Corticotropin, Corticotropin lipotropin, Corticotropin-like intermediary peptide, Gamma LPH, gamma-MSH, Lipotropin beta, Lipotropin gamma, Lipotropin, included, LPH, Melanocyte-stimulating hormone, included, Melanotropin alpha, Melanotropin beta, Melanotropin gamma, Melanotropin, included, Met-enkephalin, MSH, NPP, POC, POMC, Pomc-1, Pomc1, Pomc2, Pro ACTH endorphin, Pro opiomelanocortin, Pro-opiomelanocortin-alpha, Proopiomelanocortin, Proopiomelanocortin preproprotein, Tetracosactide.

    Background: This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

    基因ID

    5443

    途径

    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
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