ITGA2 抗体 (AA 801-900)
Quick Overview for ITGA2 抗体 (AA 801-900) (ABIN1713632)
抗原
See all ITGA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 801-900
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交叉反应
- 人
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预测反应
- Mouse,Rat,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Integrin alpha 2/CD49b
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ITGA2 (Integrin alpha 2 (ITGA2))
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别名
- Integrin alpha 2/CD49b
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背景
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Synonyms: ITGA2, Integrin alpha 2, CD49b antigen, BR, CD 49b, CD49 antigen like family member B, CD49b, CD49b, Collagen receptor, DX5 , Glycoprotein Ia deficiency included, GP Ia, GP Ia deficiency, included, GPIa, HPA 5 included, HPA5 included, Platelet alloantigen Bra, included, Platelet antigen Br, Platelet glycoprotein GPIa, Platelet glycoprotein Ia, Platelet glycoprotein Ia/Iia, Platelet membrane glycoprotein Ia, Platelet receptor for collagen, deficiency of, included, Very late activation protein 2 receptor alpha 2 subunit, VLA 2 alpha chain, VLA 2, VLA 2 subunit alpha, VLA2 alpha chain, ITA2_HUMAN.
Background: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.
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基因ID
- 3673
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UniProt
- P17301
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途径
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
抗原
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