DPPA3 抗体 (AA 101-159)
(1 reference)Quick Overview for DPPA3 抗体 (AA 101-159) (ABIN1713577)
抗原
See all DPPA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-159
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交叉反应
- 小鼠, Pig
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Stella/DPPA3
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亚型
- IgG
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anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 1-159) antibody
DPPA3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 145-179), (C-Term) antibodyDPPA3 适用: 人 WB 宿主: 兔 Polyclonal RB50716 unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 1-159) antibodyDPPA3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 134-170), (C-Term) antibodyDPPA3 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51138 unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 1-159) antibodyDPPA3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 100-150) antibodyDPPA3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Zygote arrest 1, nucleoplasmin 2, and developmentally associated protein 3 mRNA profiles throughout porcine embryo development in vitro." in: Theriogenology, Vol. 86, Issue 9, pp. 2254-2262, (2016) (PubMed).
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: "Zygote arrest 1, nucleoplasmin 2, and developmentally associated protein 3 mRNA profiles throughout porcine embryo development in vitro." in: Theriogenology, Vol. 86, Issue 9, pp. 2254-2262, (2016) (PubMed).
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- DPPA3 (Developmental Pluripotency Associated 3 (DPPA3))
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别名
- Stella/DPPA3
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背景
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Synonyms: STELLA, Developmental pluripotency-associated protein 3, Stella-related protein, DPPA3, STELLAR
Background: Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis (By similarity).
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基因ID
- 359787
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UniProt
- Q6W0C5
抗原
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