MS4A15 抗体 (AA 31-130)
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北京 101111
Quick Overview for MS4A15 抗体 (AA 31-130) (ABIN1713561)
抗原
See all MS4A15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-130
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MS4A15
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亚型
- IgG
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anti-Membrane-Spanning 4-Domains, Subfamily A, Member 15 (MS4A15) (AA 1-147) antibody
MS4A15 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D4 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 15 (MS4A15) (AA 1-147) antibodyMS4A15 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MS4A15 (Membrane-Spanning 4-Domains, Subfamily A, Member 15 (MS4A15))
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别名
- MS4A15
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背景
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Synonyms: FLJ34527, Hypothetical protein MGC35295, M4A15_HUMAN, Membrane spanning 4 domains subfamily A member 15, Membrane-spanning 4-domains subfamily A member 15, MGC35295, MS4A15.
Background: MS4A (membrane-spanning 4-domain family, subfamily A) is a large family of proteins that includes at least 26 members in mouse and humans. Flanked by amino- and carboxyl- cytoplasmic regions, MS4A family members contain four highly conserved transmembrane domains. CD20, the most well-known MS4A family member, is a B-cell-specific molecule that functions as a calcium-permeable cation channel and is known to accelerate the G0 to G1 progression induced by IGF-1. MS4A15 (membrane-spanning 4-domains, subfamily A, member 15) is a 240 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding MS4A15 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
抗原
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