Hect E3 Ubiquitin Ligase 抗体 (AA 1-100)
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北京 101111
Quick Overview for Hect E3 Ubiquitin Ligase 抗体 (AA 1-100) (ABIN1713527)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HECT E3 ubiquitin ligase
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Hect E3 Ubiquitin Ligase (LOC662402)
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别名
- HECT E3 ubiquitin ligase
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背景
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Synonyms: CEB1, CEBP1, Cyclin E binding protein 1, Cyclin-E-binding protein 1, E3 ISG15--protein ligase HERC5, HECT domain and RCC1 like domain containing protein 5, HECT domain and RCC1-like domain-containing protein 5, Hect domain and RLD 5, HECT E3 ubiquitin ligase, HERC5, HERC5_HUMAN, Herc6.
Background: HECT E3 ubiquitin ligase is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
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基因ID
- 51191
抗原
-
