Cholera Toxin beta 抗体
(1 reference)Quick Overview for Cholera Toxin beta 抗体 (ABIN1713348)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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交叉反应 （详细）
- Cholera Toxin Subunit B
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from CTXB/beta subunit Cholera Toxin
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亚型
- IgG
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应用备注
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Possible Role of the Myelinated Neural Network in the Parietal Peritoneum in Rats as a Mechanoreceptor." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 300, Issue 9, pp. 1662-1669, (2017) (PubMed).
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: "Possible Role of the Myelinated Neural Network in the Parietal Peritoneum in Rats as a Mechanoreceptor." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 300, Issue 9, pp. 1662-1669, (2017) (PubMed).
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- Cholera Toxin beta
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背景
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Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin beta chain, Cholera enterotoxin gamma chain, Cholera enterotoxin subunit B, Cholera toxin B protein, Choleragenoid, CTX B, CTXB, TOX B, TOXB, VC1456, CHTB_VIBCH.
Background: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
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基因ID
- 2613962
抗原
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