Claudin 7 抗体 (PE)
Quick Overview for Claudin 7 抗体 (PE) (ABIN1712744)
抗原
See all Claudin 7 (CLDN7) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠, 大鼠, 犬, 牛
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纯化方法
- purified by Protein A
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免疫原
- KLH conjugated synthetic peptide derived from human Claudin 7
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亚型
- IgG
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说明
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Excitation / Emission wavelength: 496nm / 578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 µg/µL
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缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4 °C for 12 months
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有效期
- 12 months
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- Claudin 7 (CLDN7)
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别名
- Claudin 7
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背景
- The Claudin superfamily consists of many structurally related proteins in humans (1). These proteins are important structural and functional components of tight junctions in paracellular transport (1,2). Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues (1). Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and Junction adhesion molecule (3). Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands (4). Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions (5). mRNA studies indicate that Claudin-7 is specifically expressed in mouse lung and kidney, but not in heart, brain, spleen, liver, skeletal muscle or testis (6). The gene encoding human Claudin-7 maps to chromosome 17p13 (7).
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基因ID
- 1366
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途径
- Hepatitis C
抗原
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