BOC 抗体 (PE)
Quick Overview for BOC 抗体 (PE) (ABIN1712708)
抗原
See all BOC 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Protein BOC
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亚型
- IgG
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应用备注
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FCM: 1:20-100
Optimal working dilution should be determined by the investigator. -
说明
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Exitation/Emission: 480,565nm/578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4 °C
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有效期
- 12 months
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- BOC (Brother Of CDO (BOC))
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别名
- Protein Boc
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背景
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BOC is a receptor-like, single pass membrane protein belonging to the cell surface molecule subfamily of the Immunoglobulin/fibronectin type-III repeat family within the immunoglobulin superfamily. It contains three fibronectin type-III domains and four Immunoglobulin-like C2-type domains in its extracellular region. The intracellular region of BOC is not required for proper function. BOC localizes to the cell membrane and is ubiquitously expressed with highest expression levels in skeletal muscle and small intestine. Its mRNA expression is down-regulated by Ras. BOC is involved in accelerating myoblast differentiation and is dependent on CDO for its activity. BOC and CDO are co-expressed in muscle precursors and are components of a receptor complex that mediates cell-cell interactions important in myogenesis. Overexpression of BOC results in enhanced differentiation of myoblast cells. In addition, BOC is a target and signaling component of the Shh pathway.
Subcellular location: Extracellular
Synonyms: Boc homolog mouse, Brother of CDO, Protein BOC, brother of CDO precursor, Protein BOC, BOC_HUMAN. -
基因ID
- 91653
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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