KIF13B 抗体 (AA 351-450) (HRP)
Quick Overview for KIF13B 抗体 (AA 351-450) (HRP) (ABIN1712558)
抗原
See all KIF13B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-450
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KIF13B
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KIF13B (Kinesin Family Member 13B (KIF13B))
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别名
- KIF13B
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背景
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Synonyms: GAKIN, Guanylate kinase associated kinesin, KI13B_HUMAN, KIAA0639, K 13B, K13B, Kinesin 13B, Kinesin family member 13B, Kinesin like protein GAKIN, Kinesin like protein K13B, Kinesin-like protein GAKIN, Kinesin-like protein K13B, OTTHUMP00000225649.
Background: KIF13B is also known as Kinesin-like protein GAKIN or GAKIN and is a 1,826 amino acid protein that is widely expressed in tissues, with highest expression in brain and kidney. KIF13B is localized to the cytoplasm, as well as to the cytoskeleton, and is thought to be a microtubule-dependent motor protein which is able to bind to a variety of proteins in order to traffic them to various locations throughout the cell. KIF13B belongs to the kinesin-like protein family and possesses three domains typical of the kinesin-like protein family, namely an N-terminal motor domain with an ATP-binding motif, an FHA domain which is known to bind diverse cargos and a large stalk domain involved in protein-protein binding. Additionally, KIF13B has a microtubule-interacting sequence which is known as the CAP-Gly domain at its C-terminus. The CAP-Gly domain is highly conserved domain among eukaryotes, and in humans, defects in the CAP-Gly domain are implicated in many diseases affecting the trafficking of vesicles, neuromuscular junctions and lysosome proliferation.
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基因ID
- 23303
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UniProt
- Q9NQT8
抗原
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