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DAPP1 抗体 (pTyr139) (HRP)

This anti-DAPP1 antibody is a 兔 多克隆 antibody detecting DAPP1 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1711786
发货至: 中国

Quick Overview for DAPP1 抗体 (pTyr139) (HRP) (ABIN1711786)

抗原

See all DAPP1 抗体
DAPP1 (Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This DAPP1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pTyr139

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human DAPP1 around the phosphorylation site of Tyr139

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DAPP1 (Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1))

    别名

    DAPP1

    背景

    Synonyms: DAPP1 phospho Y139, p-DAPP1 phospho Y139, B cell adapter molecule of 32 kDa, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa, BAM32, DAPP1, DAPP1_HUMAN, DKFZp667E0716, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, Dual adaptor of phosphotyrosine and 3 phosphoinositides, hDAPP1.

    Background: B cell adapter molecule is also designated dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC g2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.

    基因ID

    27071

    途径

    BCR Signaling
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