DOCK4 抗体 (AA 1001-1100) (HRP)
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北京 101111
Quick Overview for DOCK4 抗体 (AA 1001-1100) (HRP) (ABIN1711661)
抗原
See all DOCK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1001-1100
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DOCK4
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亚型
- IgG
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anti-Dedicator of Cytokinesis 4 (DOCK4) (AA 1867-1966) antibody
DOCK4 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Dedicator of Cytokinesis 4 (DOCK4) (AA 1867-1966) antibodyDOCK4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Dedicator of Cytokinesis 4 (DOCK4) (AA 1867-1966) antibodyDOCK4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))
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别名
- DOCK4
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背景
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Synonyms: Dedicator of cytokinesis protein 4, Dock4, DOCK4_HUMAN, KIAA0716.
Background: DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.
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基因ID
- 9732
抗原
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