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BTBD14A 抗体 (AA 401-500) (HRP)

This anti-BTBD14A antibody is a 兔 多克隆 antibody detecting BTBD14A in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1711556
发货至: 中国

Quick Overview for BTBD14A 抗体 (AA 401-500) (HRP) (ABIN1711556)

抗原

See all BTBD14A 抗体
BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

适用

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宿主

  • 32
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克隆类型

  • 33
多克隆

标记

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This BTBD14A antibody is conjugated to HRP

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 8
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    • 1
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    • 1
    • 1
    AA 401-500

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human BTBD14A

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

    别名

    BTBD14A

    背景

    Synonyms: BTB POZ domain containing 14A, BTB domain containing 14A, BTB/POZ domain containing protein 14A, BTB/POZ domain-containing protein 14A, BTBD 14A, BTBD14, NAC-2, NACC2, NACC2_HUMAN, Nucleus accumbens-associated protein 2.

    Background: BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

    基因ID

    54813

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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