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PRAM1 抗体 (AA 551-650) (HRP)

This 兔 多克隆 antibody specifically detects PRAM1 in IHC (p) 和 IHC (fro). It exhibits reactivity toward 人.
产品编号 ABIN1711399
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for PRAM1 抗体 (AA 551-650) (HRP) (ABIN1711399)

抗原

See all PRAM1 抗体
PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

适用

  • 33
  • 1

宿主

  • 31
  • 1
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克隆类型

  • 33
多克隆

标记

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This PRAM1 antibody is conjugated to HRP

应用范围

  • 13
  • 13
  • 11
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  • 7
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  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 13
    • 2
    • 1
    • 1
    AA 551-650

    原理

    PRAM1 Polyclonal Antibody, HRP Conjugated

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PRAM1

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

    别名

    PRAM1

    背景

    Synonyms: PML RAR, PML RARA regulated adaptor molecule 1, PML RARA target gene encoding an Adaptor Molecule 1, PML-RARA-regulated adapter molecule 1, PRAM 1, PRAM, PRAM-1, PRAM_HUMAN, PRAM1.

    Background: Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells. The retinoic acid-induced gene, PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis. PRAM-1 expression is hindered by expression of PML-RAR-a. The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs. PRAM-1 demonstrates expression in hematopoietic tissues and lung.

    途径

    Regulation of Leukocyte Mediated Immunity
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