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ODF2 抗体 (AA 1-100) (HRP)

This anti-ODF2 antibody is a 兔 多克隆 antibody detecting ODF2 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN1711078
发货至: 中国

Quick Overview for ODF2 抗体 (AA 1-100) (HRP) (ABIN1711078)

抗原

See all ODF2 抗体
ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))

适用

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大鼠

宿主

  • 49
  • 2
  • 1

克隆类型

  • 46
  • 6
多克隆

标记

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This ODF2 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 4
    • 2
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    • 1
    • 1
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    AA 1-100

    交叉反应

    大鼠

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ODF2/Cenexin1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))

    别名

    ODF2/Cenexin1

    背景

    Synonyms: sperm tail structural protein, 84 kDa outer dense fiber protein, Cenexin 1, Cenexin1 variant 1, KKT 4, KKT4, ODF 2, ODF 84, ODF2, ODF2/1, ODF2/2, ODF84, Outer dense fiber of sperm tail 2, Outer dense fiber of sperm tails 2, outer dense fiber of sperm tails, Outer dense fiber of sperm tails protein 2, Outer dense fiber of sperm tails, 84 kD, Outer dense fiber protein 2, Sperm outer dense fiber major protein 2, Testis specic autoantigen, ODFP2_HUMAN.

    Background: Cenexin1 is an isoform of ODF2, that unlike ODF2 is present in several somatic cell types. Cenexin1 acts as a general scaffold protein that is specifically localised to the distal/subdistal appendages of mother centrioles. Cenexin1 is required for proper localization of Plk1 to the centrosomes. This centrosomal localization of Plk1 is required for proper microtubule function. Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2. Cenexin1 is required for proper mitotic progression, depletion of Cenexin1 µLtimately leads to chromosome missegregation and apoptosis. The ODF2 (outer dense fiber 2) gene encodes both ODF2 and Cenexin1, which have very different functions. ODF2 is a major component of sperm tail outer dense fibers (ODFs). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. They may help to maintain the passive elastic structures and elastic recoil of the sperm tail, and may also modulate sperm motility.

    基因ID

    4957

    途径

    M Phase
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