HPV16 E7 抗体 (HRP)
Quick Overview for HPV16 E7 抗体 (HRP) (ABIN1710867)
抗原
See all HPV16 E7 (HPV-16 E7) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- Virus
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交叉反应 （详细）
- HPV16
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from HPV16 E7 protein
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亚型
- IgG
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anti-Human Papilloma Virus 16 E7 (HPV-16 E7) (Middle Region) antibody
HPV-16 E7 适用: Human Papillomavirus 16 (HPV-16) WB, IF (p), ELISA, FACS, IF (cc), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Human Papilloma Virus 16 E7 (HPV-16 E7) antibodyHPV-16 E7 适用: Human Papillomavirus 16 (HPV-16) WB, ELISA 宿主: 小鼠 Monoclonal 3D6F1 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
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别名
- HPV16 E7
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物质类
- Viral Protein
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背景
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Synonyms: E7, Human Papilloma Virus, Human papillomavirus type 16 E7, Human papillomavirus type 16 E7, Protein E7, Human Papillomavirus 16 E7, HPV16 E7, E7 protein HPV16, VE7_HPV16.
Background: Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90 % of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.
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基因ID
- 1489079
抗原
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