BORA 抗体 (AA 31-130) (FITC)
Quick Overview for BORA 抗体 (AA 31-130) (FITC) (ABIN1710370)
抗原
See all BORA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 31-130
-
预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human BORA
-
亚型
- IgG
-
-
anti-Protein Aurora Borealis (BORA) (AA 178-312) antibody
BORA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Aurora Borealis (BORA) (C-Term) antibodyBORA 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Aurora Borealis (BORA) (AA 320-619) antibodyBORA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Aurora Borealis (BORA) (N-Term) antibodyBORA 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Protein Aurora Borealis (BORA) (C-Term) antibodyBORA 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- BORA (Protein Aurora Borealis (BORA))
-
别名
- BORA
-
背景
-
Synonyms: Aurora borealis, bora, BORA_HUMAN, C13orf34, Chromosome 13 open reading frame 34, FLJ22624, HsBora, Protein aurora borealis, RP11-342J4.2.
Background: Aurora related kinase-1 (ARK-1) is a centrosome-associated serine/threonine kinase that regulates centrosome separation, bipolar spindle assembly and chromosome segregation during mitosis. Bora (protein aurora borealis) is a 559 amino acid protein that activates ARK-1. Bora is localized to the nucleus until mitosis is initiated, when it then translocates to the cytoplasm. This translocation is dependent on activated Cdc2, which releases Bora to bind and activate ARK-1 in the cytoplasm. Plk (polo-like kinase) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation on its N-terminus by ARK-1. It is through this mechanism that Bora and ARK-1 control cellular mitotic entry. Downregulation of the gene encoding Bora results in multipolar spindles in mitosis, a phenomenon that is also observed when ARK-1 function is blocked.
-
基因ID
- 79866
抗原
-
