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SIX2 抗体 (AA 101-200) (FITC)

This anti-SIX2 antibody is a 兔 多克隆 antibody detecting SIX2 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1710273
发货至: 中国

Quick Overview for SIX2 抗体 (AA 101-200) (FITC) (ABIN1710273)

抗原

See all SIX2 抗体
SIX2 (SIX Homeobox 2 (SIX2))

适用

  • 33
  • 6
  • 5
  • 3
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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宿主

  • 32
  • 3

克隆类型

  • 31
  • 4
多克隆

标记

  • 17
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This SIX2 antibody is conjugated to FITC

应用范围

  • 35
  • 19
  • 12
  • 12
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SIX2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SIX2 (SIX Homeobox 2 (SIX2))

    别名

    SIX2

    背景

    Synonyms: Homeobox protein SIX2, OTTHUMP00000201649, Sine oculis homeobox Drosophila homolog 2, Sine oculis homeobox homolog 2, Sine oculis homeobox homolog 2 Drosophila, SIX homeobox 2, Six2, SIX2_HUMAN.

    Background: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six2, Six4 (AREC3) and Six5 bind to the same DNA sequence, indicating that they may regulate the same target genes. Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, such as myogenin. It has been demonstrated that alterations to homeobox-containing genes may result in cancer. Six1 expression has been shown to be absent or low in normal adult tissues, although it is expressed in several tumor types, including breast carcinoma. Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint. Six2 is highly expressed in fetal tissues but expression is limited in adult tissues.

    基因ID

    10736

    途径

    Protein targeting to Nucleus
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