IQSEC2 抗体 (AA 851-950) (FITC)
Quick Overview for IQSEC2 抗体 (AA 851-950) (FITC) (ABIN1709553)
抗原
See all IQSEC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 851-950
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human IQSEC2
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亚型
- IgG
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anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 451-484) antibody
IQSEC2 适用: 人 WB 宿主: 兔 Polyclonal RB52674 unconjugated
anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 1-949) antibodyIQSEC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 351-400) antibodyIQSEC2 适用: 小鼠, 人, 大鼠, Cow, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
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别名
- IQSEC2
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背景
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Synonyms: BRAG1, IQ mot and SEC7 domain-containing protein 2, IQEC2_HUMAN, Iqsec2, KIAA0522, mKIAA0522, MRX1, RP11-258C19.1.
Background: IQSEC2 is a 1,478 amino acid protein that belongs to the BRAG family and contains one IQ domain, one PH domain and a SEC7 domain. Localizing to the cytoplasm, IQSEC2 is expressed in brain, kidney and small intestine, with weaker levels of expression in placenta, pancreas, ovary, prostate and liver. IQSEC2 is a component of the postsynaptic density at excitatory synapses, and interacts with ARF family members as a guanine nucleotide exchange factor. Through the activation of ARF substrates, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization. The gene encoding IQSEC2 maps to the human X chromosome. Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), a condition characterized by decreased intellectual function. IQSEC2 exists as three isoforms due to alternative splicing events.
抗原
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