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EYA2 抗体 (AA 201-300) (Cy7)

This anti-EYA2 antibody (ABIN1708637) is a Rabbit Polyclonal antibody detecting EYA2 in WB, IF (cc), IF (p). Suitable for Rat.
产品编号 ABIN1708637
发货至: 中国

Quick Overview for EYA2 抗体 (AA 201-300) (Cy7) (ABIN1708637)

抗原

See all EYA2 抗体
EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))

适用

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大鼠

宿主

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克隆类型

  • 45
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多克隆

标记

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This EYA2 antibody is conjugated to Cy7

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 201-300

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EYA2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))

    别名

    EYA2

    背景

    Synonyms: EAB 1, EAB1, EYA 2, EYA2, EYA2_HUMAN, eyes absent 2 homolog Drosophila, Eyes absent homolog 2, Translation of this uORF probably lowers the translation efficiency of EYA2.

    Background: A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.

    基因ID

    2139
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