GCS1 抗体 (AA 51-150) (Cy7)
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Quick Overview for GCS1 抗体 (AA 51-150) (Cy7) (ABIN1708344)
抗原
See all GCS1 (MOGS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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预测反应
- Human,Mouse,Rat,Dog
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GCS1
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亚型
- IgG
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anti-Mannosyl-Oligosaccharide Glucosidase (MOGS) (AA 60-320) antibody
MOGS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mannosyl-Oligosaccharide Glucosidase (MOGS) antibodyMOGS 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mannosyl-Oligosaccharide Glucosidase (MOGS) (AA 144-193) antibodyMOGS 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Mannosyl-Oligosaccharide Glucosidase (MOGS) antibodyMOGS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mannosyl-Oligosaccharide Glucosidase (MOGS) (N-Term) antibodyMOGS 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GCS1 (MOGS) (Mannosyl-Oligosaccharide Glucosidase (MOGS))
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别名
- GCS1
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背景
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Synonyms: EC 3.2.1.106, glucosidase I, Mannosyl oligosaccharide glucosidase, Mannosyl-oligosaccharide glucosidase, Mogs, MOGS_HUMAN, Processing A glucosidase I, Processing A-glucosidase I.
Background: Glycosylation of asparagine residues in Asn-X-Ser/Thr motifs in proteins commonly occur in the lumen of the endoplasmic reticulum (ER). Glucosidase I catalyzes the first step in the N-linked oligosaccharide processing pathway. It specifically removes the distal alpha 1,2-linked glucose residue from the Glc3-Man9-GlcNAc2 oligosaccharide precursor. Glucosidase I contains a short cytosolic tail, a single pass transmembrane domain and a large C-terminal catalytic domain located on the luminal side of the ER. Mutations in the gene encoding Glucosidase I result in the congenital disorder glycosylation (CDG-IIb), which is characterized by generalized hypotonia, dysmorphic features, hepatomegaly, hypoventilation, feeding problems, seizures and death. Two point mutations in the Glucosidase I gene have been identified and result in amino acid substitutions, namely Arg486Thr and Phe652Leu, that affect polypeptide folding and active site formation.
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基因ID
- 7841
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途径
- SARS-CoV-2 Protein Interactome
抗原
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