TMC8 抗体 (AA 301-400) (Cy7)
Quick Overview for TMC8 抗体 (AA 301-400) (Cy7) (ABIN1708252)
抗原
See all TMC8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human EVER2/TMC8
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亚型
- IgG
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anti-Transmembrane Channel-Like 8 (TMC8) (C-Term) antibody
TMC8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Channel-Like 8 (TMC8) (C-Term) antibodyTMC8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Channel-Like 8 (TMC8) (C-Term) antibodyTMC8 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Channel-Like 8 (TMC8) (AA 143-192) antibodyTMC8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Channel-Like 8 (TMC8) (Center) antibodyTMC8 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- TMC8 (Transmembrane Channel-Like 8 (TMC8))
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别名
- EVER2/TMC8
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背景
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Synonyms: epidermodysplasia verrucormis 2, Epidermodysplasia verrucormis protein 2, EV2, EVIN2, FLJ40668, FLJ43684, MGC102701, MGC40121, TMC8, Transmembrane channel like protein 8, TMC8_HUMAN.
Background: Transmembrane channel-like protein 8 (TMC8), also known as Epidermodysplasia verruciformis protein 2 (EVER2), is a 726 amino acid member of the TMC family of proteins. Localized to the endoplasmic reticulum membrane, TMC8 is thought to form a transmembrane channel-like protein with eight predicted transmembrane domains and three leucine zipper motifs. Mutations in the genes encoding TMC8 and TMC6, another member of the TMC family, have been shown to cause epidermodysplasia verruciformis (EV), an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. Infection by HPVs lead to persistent wart-like or macular lesions. TMC8 is expressed in placenta, prostate and testis, and three named isoforms exist as a result of alternative splicing events.
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基因ID
- 147138
抗原
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