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GAD65+GAD67 (AA 351-450) 抗体 (Cy7)

This anti- antibody is a 兔 多克隆 antibody detecting in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN1708068
发货至: 中国

Quick Overview for GAD65+GAD67 (AA 351-450) 抗体 (Cy7) (ABIN1708068)

抗原

GAD65+GAD67

适用

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  • 13
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  • 1
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小鼠

宿主

  • 26
  • 1
  • 1

克隆类型

  • 26
  • 1
多克隆

标记

  • 7
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  • 1
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Cy7

应用范围

  • 20
  • 12
  • 12
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  • 5
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  • 4
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 4
    • 1
    • 1
    AA 351-450

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GAD65

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GAD65+GAD67

    别名

    GAD65 + GAD67

    背景

    Synonyms: Glutamate decarboxylase 2, GAD2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform, Glutamate decarboxylase 1, GAD1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform

    Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.

    基因ID

    25722571

    UniProt

    Q05329, Q99259
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