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ARID1B 抗体 (AA 1501-1600) (Cy7)

This Cy7-conjugated 兔 多克隆 anti-ARID1B antibody specifically detects ARID1B in WB, IF (cc) 和 IF (p). The antibody is reactive with 小鼠 samples.
产品编号 ABIN1707929
发货至: 中国
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Quick Overview for ARID1B 抗体 (AA 1501-1600) (Cy7) (ABIN1707929)

抗原

See all ARID1B 抗体
ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))

适用

  • 36
  • 18
  • 12
  • 2
  • 1
  • 1
  • 1
小鼠

宿主

  • 44
  • 6

克隆类型

  • 43
  • 7
多克隆

标记

  • 20
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ARID1B antibody is conjugated to Cy7

应用范围

  • 32
  • 15
  • 12
  • 12
  • 12
  • 11
  • 9
  • 5
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1501-1600

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ARID1B

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))

    别名

    ARID1B

    背景

    Synonyms: OSA2, 6A3-5, DAN15, MRD12, P250R, BRIGHT, BAF250B, ELD/OSA1, AT-rich interactive domain-containing protein 1B, ARID domain-containing protein 1B, BRG1-associated factor 250b, BRG1-binding protein hELD/OSA1, Osa homolog 2, hOsa2, ARID1B, KIAA1235

    Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.

    基因ID

    57492

    UniProt

    Q8NFD5
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