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SH2B3 抗体 (AA 161-260) (Cy7)

This Cy7-conjugated 兔 多克隆 anti-SH2B3 antibody specifically detects SH2B3 in WB, IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN1707748
发货至: 中国
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北京 101111
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Quick Overview for SH2B3 抗体 (AA 161-260) (Cy7) (ABIN1707748)

抗原

See all SH2B3 抗体
SH2B3 (SH2B Adaptor Protein 3 (SH2B3))

适用

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宿主

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克隆类型

  • 27
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多克隆

标记

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This SH2B3 antibody is conjugated to Cy7

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
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    AA 161-260

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Monkey

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human LNK

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SH2B3 (SH2B Adaptor Protein 3 (SH2B3))

    别名

    LNK

    背景

    Synonyms: IDDM20,Lymphocyte adapter protein,Lymphocyte specic adapter protein,Lymphocyte specic adapter protein Lnk,Lymphocyte-specic adapter protein Lnk,SH2B adapter protein 3,SH2B adaptor protein 3,Sh2b3,SH2B3_HUMAN,Signal transduction protein Lnk.

    Background: APS (adapter molecule containing PH and SH2 domains), SH2-B and Lnk compose a family of adapter proteins, which contain a pleckstrin homology (PH) domain, an SH2 domain and a tyrosine phosphorylation site. Stimulation of B cell receptor (BCR) or T cell receptor (TCR) results in the phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of BCR, TCR and several substrates. APS, SH2-B and Lnk may bind to the ITAM domain of BCR and TCR. Lnk is tyrosine phosphorylated in response to TCR stimulation and APS has been shown to be tyrosine phosphorylated in response to BCR stimulation.

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