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AFAP1L2 抗体 (Cy7)

This anti-AFAP1L2 antibody (ABIN1707587) is a Rabbit Polyclonal antibody detecting AFAP1L2 in WB. Suitable for Human, Mouse, Rat.
产品编号 ABIN1707587
发货至: 中国

Quick Overview for AFAP1L2 抗体 (Cy7) (ABIN1707587)

抗原

See all AFAP1L2 抗体
AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This AFAP1L2 antibody is conjugated to Cy7

应用范围

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Western Blotting (WB)
  • 交叉反应

    小鼠

    预测反应

    Human,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human AFAP1L2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))

    别名

    Afap1l2

    背景

    Synonyms: KIAA1914, XB130, Actin filament-associated protein 1-like 2, AF1L2_HUMAN, AFAP1-like protein 2, afap1l2.

    Background: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.

    途径

    EGFR Signaling Pathway
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