AFAP1L2 抗体 (Cy7)
Quick Overview for AFAP1L2 抗体 (Cy7) (ABIN1707587)
抗原
See all AFAP1L2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human AFAP1L2
-
亚型
- IgG
-
-
anti-Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (AA 674-818) antibody
AFAP1L2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2H6D1 unconjugated
anti-Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (AA 66-115) antibodyAFAP1L2 适用: 人, 小鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (AA 1-300) antibodyAFAP1L2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (N-Term) antibodyAFAP1L2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (C-Term) antibodyAFAP1L2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IF(IHC-P) 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
-
别名
- Afap1l2
-
背景
-
Synonyms: KIAA1914, XB130, Actin filament-associated protein 1-like 2, AF1L2_HUMAN, AFAP1-like protein 2, afap1l2.
Background: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.
-
途径
- EGFR Signaling Pathway
抗原
-
