KRT8 抗体 (pSer74) (Cy7)
Quick Overview for KRT8 抗体 (pSer74) (Cy7) (ABIN1707565)
抗原
See all KRT8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer74
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human CK8 around the phosphorylation site of Ser74
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KRT8 (Keratin 8 (KRT8))
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别名
- Cytokeratin 8
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背景
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Synonyms: Cytokeratin 8 phospho S74, p-Cytokeratin 8 phospho S74, card2, Cardiac autoantigen 2 120kD, CK 8, CK-8, ck8, Cyk 8, cyk8, CYKER, Cytokeratin 8, Cytokeratin endo A, Cytokeratin-8, Cytokeratin8, DreK8, EndoA, k0, CYK8, k2c8, K2C8_HUMAN, k8, Keratin 8, Keratin type ii cytoskeletal 8, Keratin, type II cytoskeletal 8, Keratin-8, Keratin8, KO, Krt 2.8, Krt 8, krt8, KRT-8, MGC118110, MGC174782, MGC53564, MGC85764, sb:cb186, Type-II keratin Kb8.
Background: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
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基因ID
- 3856
抗原
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