MED23 抗体 (AA 401-500) (Cy7)
Quick Overview for MED23 抗体 (AA 401-500) (Cy7) (ABIN1707552)
抗原
See all MED23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-500
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预测反应
- Human,Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DRIP130/CRSP130
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亚型
- IgG
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anti-Mediator Complex Subunit 23 (MED23) (AA 1014-1368) antibody
MED23 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 23 (MED23) antibodyMED23 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 23 (MED23) (N-Term) antibodyMED23 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 23 (MED23) (N-Term) antibodyMED23 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 23 (MED23) (AA 531-630) antibodyMED23 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Mediator Complex Subunit 23 (MED23) (N-Term) antibodyMED23 适用: 人, 大鼠, 小鼠, 马, 兔, Cow, 豚鼠, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 23 (MED23) (AA 1-50) antibodyMED23 适用: 人, 大鼠, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 23 (MED23) (AA 897-916) antibodyMED23 适用: 人 ELISA, WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- MED23 (Mediator Complex Subunit 23 (MED23))
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别名
- DRIP130/CRSP130
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背景
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Synonyms: 130 kDa transcriptional co activator, 133 kDa transcriptional co activator, Activator recruited cofactor 130 kDa component, Activator-recruited cofactor 130 kDa component, ARC 130, ARC130, Cofactor required for Sp1 transcriptional activation subunit 3 130 kDa, Cofactor required for Sp1 transcriptional activation subunit 3 130 kDa mediator, Cofactor required for Sp1 transcriptional activation subunit 3, CRSP 130, CRSP 130 kD subunit, CRSP 133, CRSP 3, CRSP complex subunit 3, CRSP130, CRSP133, CRSP3, CRSP3 protein, DKFZp434H0117, DRIP 130, DRIP130, hSur-2, KIAA1216, MED 23, MED23, MED23_HUMAN, Mediator complex subunit 23, Mediator of RNA polymerase II transcription subunit 23, Protein sur-2 homolog, SUR 2, SUR2, Transcriptional co activator CRSP 130, Transcriptional co activator CRSP130, Transcriptional coactivator CRSP130, Vitamin D3 receptor interacting protein, Vitamin D3 receptor interacting protein complex 130 kDa component, Vitamin D3 receptor-interacting protein complex 130 kDa component.
Background: In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1 (2). CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits (3). Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS (4). CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins (2,5). CRSP subunits also associate with larger multimeric coactivaor complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription (6,7).
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基因ID
- 9439
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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