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CHI3L2 抗体 (AA 121-220) (Cy7)

This anti-CHI3L2 antibody is a 兔 多克隆 antibody detecting CHI3L2 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1707479
发货至: 中国

Quick Overview for CHI3L2 抗体 (AA 121-220) (Cy7) (ABIN1707479)

抗原

See all CHI3L2 抗体
CHI3L2 (Chitinase 3-Like 2 (CHI3L2))

适用

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宿主

  • 45
  • 5

克隆类型

  • 47
  • 3
多克隆

标记

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This CHI3L2 antibody is conjugated to Cy7

应用范围

  • 40
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
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    • 1
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    • 1
    • 1
    AA 121-220

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human YKL39/CHI3L2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CHI3L2 (Chitinase 3-Like 2 (CHI3L2))

    别名

    YKL39/CHI3L2

    背景

    Synonyms: CH3L2_HUMAN, CHI3L2, Chitinase 3 like 2, Chitinase-3-like protein 2, Chondrocyte protein 39, OTTHUMP00000014028, YKL 39, YKL-39, YKL39.

    Background: YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases. Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), YKL-39 binds glycan structures with high affinity. Although related to bacterial chitinases, YKL-39 lacks the characteristic glutamate active site and, thus, does not have enzymatic chitinase activity. Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid joint disease. Additionally, YKL-39 is upregulated in early degenerative cartilage diseases (such as RA) and may be a marker of chondrocyte activation in these autoimmune conditions.

    基因ID

    7690
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