BCL6B 抗体 (AA 141-440) (Cy7)
Quick Overview for BCL6B 抗体 (AA 141-440) (Cy7) (ABIN1707263)
抗原
See all BCL6B 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 141-440
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                                            预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic peptide derived from human BCL6B
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- 
                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))
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                                            别名
- BCL6B
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                                            背景
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                        Synonyms: B cell CLL/lymphoma 6, member B zinc finger protein, B-cell CLL/lymphoma 6, member B zinc finger protein, BAZF, Bcl6 associated zinc finger protein, Bcl6-associated zinc finger protein, ZBTB28, Zinc finger protein 62, ZNF62. Background: Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NF_B expression, thereby inhibiting NF_B-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. 
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                                            途径
- BCR Signaling
 抗原
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