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BCL6B 抗体 (AA 141-440) (Cy7)

This anti-BCL6B antibody (ABIN1707263) is a Rabbit Polyclonal antibody detecting BCL6B in IF (cc), IF (p). Suitable for Human.
产品编号 ABIN1707263
发货至: 中国

Quick Overview for BCL6B 抗体 (AA 141-440) (Cy7) (ABIN1707263)

抗原

See all BCL6B 抗体
BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))

适用

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宿主

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克隆类型

  • 30
多克隆

标记

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This BCL6B antibody is conjugated to Cy7

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 141-440

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human BCL6B

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))

    别名

    BCL6B

    背景

    Synonyms: B cell CLL/lymphoma 6, member B zinc finger protein, B-cell CLL/lymphoma 6, member B zinc finger protein, BAZF, Bcl6 associated zinc finger protein, Bcl6-associated zinc finger protein, ZBTB28, Zinc finger protein 62, ZNF62.

    Background: Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NF_B expression, thereby inhibiting NF_B-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.

    途径

    BCR Signaling
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