GALM 抗体 (AA 251-342) (Cy5)
Quick Overview for GALM 抗体 (AA 251-342) (Cy5) (ABIN1705135)
抗原
See all GALM 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 251-342
-
交叉反应
- 大鼠
-
预测反应
- Human,Mouse,Cow,Sheep,Pig,Horse
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human GALM/Galactose mutarotase
-
亚型
- IgG
-
-
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- GALM (Galactose Mutarotase (Aldose 1-Epimerase) (GALM))
-
别名
- GALM/Galactose mutarotase
-
背景
-
Synonyms: Aldose 1 epimerase, Aldose 1-epimerase, BLOCK25, Galactomutarotase, Galactose mutarotase, Galm, GALM_HUMAN, IBD1.
Background: Galactose Mutarotase is a member of the aldose epimerase family and is involved in hexose metabolism. Through its catalytic activity, Galactose Mutarotase converts beta-aldose to alpha-aldose on several sugars, including D-glucose, L-arabinose and D-xylose. Found in the cytoplasm of most cells, Galactose Mutarotase plays a key role in galactose metabolism by catalyzing the conversion of beta-D-galactose to alpha-D-galactose. The enzyme contains two residues, Glu 304 and His 170, that are critical for catalysis, as well as His 96 and Asp 243, which are important for proper substrate recognition by the active site. No known diseases have been associated with mutations in the Galactose Mutarotase gene, although inhibition of Galactose Mutarotase activity could potentially be associated with a build-up of unmetabolized sugars during metabolism.
-
基因ID
- 130589
抗原
-