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RRM2 抗体 (AA 151-250) (Cy5)

This anti-RRM2 antibody is a 兔 多克隆 antibody detecting RRM2 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1704987
发货至: 中国

Quick Overview for RRM2 抗体 (AA 151-250) (Cy5) (ABIN1704987)

抗原

See all RRM2 抗体
RRM2 (Ribonucleotide Reductase M2 (RRM2))

适用

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宿主

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克隆类型

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多克隆

标记

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This RRM2 antibody is conjugated to Cy5

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 9
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    • 1
    AA 151-250

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human RRM2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    RRM2 (Ribonucleotide Reductase M2 (RRM2))

    别名

    RRM2

    背景

    Synonyms: R2, Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase M2 subunit, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit, RIR2_HUMAN, RR2, RR2M, RRM2.

    Background: Ribonucleotide reductase is essential for the production and maintenance of the level of deoxyribonucleoside triphosphates (dNTPs) required for DNA synthesis. It is an enzymatic complex consisting of two nonidentical subunits, R1 and R2, which are inactive separately. R2, the smaller subunit, is localized to the cytoplasm. R2 is the limiting factor of the catalytic activity of the ribonucleotide reductase enzymatic complex. R2 expression is strictly correlated to the S-phase of the cell cycle, whereas R1 remains constant throughout all phases of the cell cycle. While R2 seems to be involved solely in the maintenance of dNTPs for DNA replication, a similar protein, p53R2, has been shown to be responsible for the production of dNTPs in response to DNA damage.

    基因ID

    6241

    途径

    Mitotic G1-G1/S Phases
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