GUCY1A1 抗体 (AA 301-400) (Cy5)
Quick Overview for GUCY1A1 抗体 (AA 301-400) (Cy5) (ABIN1704947)
抗原
See all GUCY1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 1
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亚型
- IgG
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anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 22-214) antibody
GUCY1A1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3G6B2 unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 20-152) antibodyGUCY1A1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 269-300), (N-Term) antibodyGUCY1A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB07757 unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) antibodyGUCY1A1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 1-690) antibodyGUCY1A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 41-140) antibodyGUCY1A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 1-120) antibodyGUCY1A1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 301-400) antibodyGUCY1A1 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (Internal Region) antibodyGUCY1A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 1-690) antibodyGUCY1A1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))
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背景
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Synonyms: GUCA3, MYMY6, GC-SA3, GUC1A3, GUCSA3, GUCY1A1, Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, GCS-alpha-1, Soluble guanylate cyclase large subunit, GUCY1A3
Background: Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
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基因ID
- 2982
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UniProt
- Q02108
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途径
- Myometrial Relaxation and Contraction
抗原
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