GEM 抗体 (AA 201-296) (Cy5)
Quick Overview for GEM 抗体 (AA 201-296) (Cy5) (ABIN1704918)
抗原
See all GEM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-296
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GEM
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亚型
- IgG
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anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (AA 219-270) antibody
GEM 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Hamster, 猴, Pig, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (C-Term) antibodyGEM 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (C-Term) antibodyGEM 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (AA 1-150) antibodyGEM 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (AA 34-46) antibodyVerified GEM 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (AA 1-100) antibodyGEM 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B12 unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (N-Term) antibodyGEM 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (N-Term) antibodyGEM 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (AA 1-296) antibodyGEM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-GTP Binding Protein Overexpressed in Skeletal Muscle (GEM) (AA 35-84) antibodyGEM 适用: 人, 小鼠, 犬, Cow, 豚鼠, 马, 兔, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GEM (GTP Binding Protein Overexpressed in Skeletal Muscle (GEM))
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别名
- GEM
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背景
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Synonyms: GTP binding mitogen induced T cell protein, GTP binding protein expressed in mitogen stimulated T cells, GTP binding protein GEM, GTP binding protein overexpressed in skeletal muscle, Kinase inducible Ras like protein, KIR, MGC26294, RAS like protein KIR, GEM_HUMAN.
Background: Gem belongs to the Rad/Gem/Kir (RGK) subfamily of Ras-related GTPases, which lack typical C-terminal amino acid motifs for isoprenylation. Rad and Gem bind calmodulin in a Ca2+-dependent manner via this C-terminal extension, involving residues 278297 in human Rad. High intracellular Gem levels, which interact with intact microtubules and microfilaments, promote profound changes in cell morphology. Ectopic Gem expression is sufficient to stimulate cell flattening and neurite extension in N1E-115 and SH-SY5Y neuroblastoma cells, suggesting a role for Gem in cytoskeletal rearrangement and/or morphological differentiation of neurons. Gem was also observed in developing trigeminal nerve ganglia in 12.5 day mouse embryos, demonstrating that Gem expression is a property of normal ganglionic development. The interaction of Gem with beta-subunits regulates Ca2+ channel expression at the cell surface. The human Gem gene maps to chromosome ,8q22.1.
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基因ID
- 2669
抗原
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