EYA4 抗体 (AA 301-400) (Cy5)
Quick Overview for EYA4 抗体 (AA 301-400) (Cy5) (ABIN1704870)
抗原
See all EYA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human EYA4
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亚型
- IgG
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anti-Eyes Absent Homolog 4 (EYA4) (AA 153-224) antibody
EYA4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 4 (EYA4) (AA 1-30), (C-Term) antibodyEYA4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23878 unconjugated
anti-Eyes Absent Homolog 4 (EYA4) (C-Term) antibodyEYA4 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 4 (EYA4) (N-Term) antibodyEYA4 适用: 人, 兔, 豚鼠, 小鼠, 猴, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- EYA4 (Eyes Absent Homolog 4 (EYA4))
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别名
- EYA4
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背景
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Synonyms: CMD1J, Deafness, autosomal dominant 10, DFNA 10, DFNA10, dJ78N10.1 eyes absent Drosophila homolog 4, dJ78N10.1 eyes absent, EYA 4, eya4, EYA4_HUMAN, Eyes absent 4, Eyes absent homolog 4 Drosophila, Eyes absent homolog 4, HGNC:3522, OTTHUMP00000040267.
Background: A gene of chromosome 6q23 encodes the 640 amino acid protein, EYA4 (eyes absent) (1). EYA is one of four members of the eyes absent family (1). A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family (1). EYA4 is expressed in the craniofacial mesenchyme, the dermamyotome, and the limb (1). The conserved region in other EYA proteins interacts with SIX, DACH, and G-proteins, which regulate transcription in early embryonic development (1,2,3,4). SIX translocates EYA1-3 to the nucleus, and G-proteins can stop this interaction (3,4). Premature stop codon mutations in EYA4 cause postlingual, progressive autosomal dominant hearing loss in humans (2). This shows that EYA4 is also vital to the mature organ of Corti (2). EYA4 may cause oculo-dento-digital syndrome, based on its expression pattern and map postion (1).
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基因ID
- 2070
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途径
- Sensory Perception of Sound
抗原
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