GLDC 抗体 (AA 51-150) (Cy5)
Quick Overview for GLDC 抗体 (AA 51-150) (Cy5) (ABIN1704581)
抗原
See all GLDC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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预测反应
- Human,Mouse,Rat,Dog,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GLDC
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亚型
- IgG
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anti-Glycine Dehydrogenase (GLDC) (AA 81-268) antibody
GLDC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycine Dehydrogenase (GLDC) (AA 36-290) antibodyGLDC 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycine Dehydrogenase (GLDC) antibodyGLDC 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycine Dehydrogenase (GLDC) (AA 627-833) antibodyGLDC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycine Dehydrogenase (GLDC) (AA 868-984) antibodyGLDC 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycine Dehydrogenase (GLDC) antibodyGLDC 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Glycine Dehydrogenase (GLDC) (AA 49-77), (N-Term) antibodyGLDC 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB23981 unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GLDC (Glycine Dehydrogenase (GLDC))
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别名
- GLDC
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背景
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Synonyms: GCE, GCSP, GCSP_HUMAN, GLDC, Glycine cleavage system P protein, glycine cleavage system protein P, Glycine decarboxylase, glycine decarboxylase P protein, Glycine dehydrogenase decarboxylating mitochondrial, Glycine dehydrogenase [decarboxylating], mitochondrial, Gycine dehydrogenase decarboxylating, HYGN1, MGC138198, MGC138200, NKH.
Background: The glycine cleavage system is comprised of AMT (known as Protein T), GCSH (known as Protein H), DLD (known as Protein L) and GLDC (known as Protein P), all of which work together to catalyze the cleavage and degradation of glycine. GLDC (glycine dehydrogenase ), also known as GCE, GCSP (glycine cleavage system P protein) or HYGN1, is a 1,020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family. GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T. GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor. Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.
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基因ID
- 2731
抗原
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