CSPS (AA 201-295) 抗体 (Cy5)
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- 抗原
- CSPS
- 抗原表位
- AA 201-295
- 适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Cy5
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Cow,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CSPS
- 亚型
- IgG
-
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- CSPS
- 背景
-
Synonyms: Aryl sulfotransferase 1A3/1A4, Aryl sulfotransferase, Catecholamine Sulfating Phenol Sulfotransferase, Catecholamine-sulfating phenol sulfotransferase, Dopamine specic sulfotransferase, FLJ54864, HAST, HAST3, M PST, M-PST, Monoamine preferring sulfotransferase, Monoamine sulfating phenosulfotransferase, monoamine-preferring, Monoamine-sulfating phenol sulfotransferase, MPST, Phenol sulfotransferase 1A5, Placental estrogen sulfotransferase, ST1A3/ST1A4, ST1A3_HUMAN, ST1A5, STM, Sulfokinase, Sulfotransferase 1A3/1A4, Sulfotransferase, Sulfotransferase family cytosolic 1A phenol preferring member 3, Sulfotransferase family cytosolic 1A phenol preferring member 4, Sulfotransferase monoamine preferring, SULT1A 3, SULT1A4, Thermolabile monoamine M form phenol sulfotransferase, Thermolabile phenol sulfotransferase, TL PST, TL-PST, TLPST.
Background: Cysteine string proteins (CSPs) are synaptic vesicle-associated, secretory vesicle proteins that are involved in Ca2+-regulated exocytosis of synaptic vesicles and modulation of presynaptic transmembrane calcium fluxes in neuroendocrine and endocrine cell types. CSP contains a J-domain that binds HSP 70/HSC 70 chaperone ATPases and a membrane-targeting, palmitoylated cysteine-rich string region. CSPs may act as molecular chaperones in synapses, and mediate conformational folding of components of the vesicular exocytotic machinery. CSP is involved in the fine tuning of neurotransmission through its interaction with receptor-coupled trimeric GTP binding proteins (G proteins) and N-type Ca2+ channels. Two variants of CSP have been described: CSP1, and the 31 amino acid, C-terminally truncated isoform, CSP2. Subcellular fractionation of insulinoma cells shows CSP1 in granular fractions, while the membrane and cytosol fractions contain predominantly CSP2. The fractions also contain additional proteins, presumably CSP dimers. Furthermore, in various mammalian cell lines (including rat brain) CSP1 expression predominates CSP2 expression.
- 基因ID
- 101060714
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