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GATA3 抗体 (pSer162) (Cy5)

This anti-GATA3 antibody is a 兔 多克隆 antibody detecting GATA3 in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN1704397
发货至: 中国

Quick Overview for GATA3 抗体 (pSer162) (Cy5) (ABIN1704397)

抗原

See all GATA3 抗体
GATA3 (GATA Binding Protein 3 (GATA3))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This GATA3 antibody is conjugated to Cy5

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    pSer162

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human GATA3 around the phosphorylation site of Ser162

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GATA3 (GATA Binding Protein 3 (GATA3))

    别名

    GATA3

    背景

    Synonyms: GATA3 phospho S162, p-GATA3 phospho S162, GATA3 phospho Ser162, p-GATA3 Ser162, GATA 3, GATA3, GATA-3, GATA binding factor 3, GATA binding protein 3, HDR, MGC2346, MGC5199, MGC5445, Trans acting T cell specic transcription factor GATA 3, GATA3_HUMAN, Trans-acting T-cell-specic transcription factor GATA-3, GATA-binding factor 3.

    Background: Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.

    基因ID

    2625

    途径

    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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