FYB 抗体 (AA 501-600) (Cy5)
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北京 101111
Quick Overview for FYB 抗体 (AA 501-600) (Cy5) (ABIN1704292)
抗原
See all FYB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FYB/ADAP
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亚型
- IgG
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anti-FYN-Binding Protein (FYB) antibody
FYB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 678-829) antibodyFYB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (Internal Region) antibodyVerified FYB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 39-88) antibodyFYB 适用: 人, 小鼠, 马, Pig, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 646-695) antibodyFYB 适用: 人, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (N-Term) antibodyFYB 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FYB (FYN-Binding Protein (FYB))
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别名
- FYB/ADAP
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背景
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Synonyms: ADAP, Adhesion and degranulation promoting adaptor protein, FYB 120/130, Fyb, FYB-120/130, FYB_HUMAN, FYN binding protein, FYN T binding protein, FYN-binding protein, FYN-T-binding protein, p120/p130, PRO0823, SLAP 130, SLAP-130, SLAP130, SLP 76 associated phosphoprotein, SLP-76-associated phosphoprotein, SLP76 associated phosphoprotein.
Background: Fyb (Fyn binding protein) and the anchoring proteins SKAP55 (src kinase-associated phosphoprotein) and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn (13). SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells (13). SKAP55 contains an amino-terminal pleckstrin homology domain and a carboxy-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY) (4,5). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain (1,2). SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation (6). The human Fyb gene maps to chromosome 5p13.1 and encodes a 783 amino acid protein (7).
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基因ID
- 2533
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途径
- TCR Signaling, Protein targeting to Nucleus
抗原
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