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Aconitase 1 抗体 (pSer711) (Cy5)

This anti-Aconitase 1 antibody is a 兔 多克隆 antibody detecting Aconitase 1 in WB, IF (p) 和 IF (cc). Suitable for 人.
产品编号 ABIN1704135
发货至: 中国
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Quick Overview for Aconitase 1 抗体 (pSer711) (Cy5) (ABIN1704135)

抗原

See all Aconitase 1 (ACO1) 抗体
Aconitase 1 (ACO1)

适用

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宿主

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克隆类型

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  • 14
多克隆

标记

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This Aconitase 1 antibody is conjugated to Cy5

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

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    pSer711

    预测反应

    Human,Mouse,Rat,Cow,Sheep,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Aconitase 1 around the phosphorylation site of Ser711 [YG(p-S)RR]

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Aconitase 1 (ACO1)

    别名

    Aconitase 1

    背景

    Synonyms: Aconitase 1 phospho S711, p-Aconitase 1 phospho S711, ACO 1, ACO1, ACOC_HUMAN, Aconitase 1 soluble, Aconitase, Aconitase1, Aconitate hydratase, ACONS, Citrate hydro lyase, Citrate hydro-lyase, Cytoplasmic aconitate hydratase, Ferritin repressor protein, IRE BP 1, IRE-BP 1, IREB 1, IREB1, IREBP, IREBP1, Iron regulatory protein 1, Iron responsive element binding protein 1, Iron-responsive element-binding protein 1, IRP 1, IRP1, OTTHUMP00000045233.

    Background: Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins, iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IREBP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.

    基因ID

    48

    途径

    Transition Metal Ion Homeostasis
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