NOB1 抗体 (Cy5)
Quick Overview for NOB1 抗体 (Cy5) (ABIN1703993)
抗原
See all NOB1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NOB1
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亚型
- IgG
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anti-RNA-Binding Protein NOB1 (NOB1) (AA 103-229) antibody
NOB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RNA-Binding Protein NOB1 (NOB1) (AA 1-230) antibodyNOB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RNA-Binding Protein NOB1 (NOB1) (C-Term) antibodyNOB1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RNA-Binding Protein NOB1 (NOB1) (AA 326-375) antibodyNOB1 适用: 人, 小鼠, Cow, 犬, 马, 兔, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-RNA-Binding Protein NOB1 (NOB1) (AA 35-84) antibodyNOB1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig, Hamster, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RNA-Binding Protein NOB1 (NOB1) antibodyNOB1 适用: Saccharomyces cerevisiae WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NOB1 (RNA-Binding Protein NOB1 (NOB1))
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别名
- NOB1
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背景
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Synonyms: Adenocarcinoma antigen recognized by T lymphocytes 4, ART4, MST158, MSTP158, Nin one binding protein, NIN1/RPN12 binding protein 1 homolog S. cerevisiae, nob1, NOB1_HUMAN, NOB1P, Phosphorylation regulatory protein HP-10, Protein ART-4, Protein ART4, PSMD8 binding protein 1, PSMD8BP1, RNA binding protein NOB1, RNA-binding protein NOB1.
Background: NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.
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基因ID
- 28987
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途径
- Protein targeting to Nucleus
抗原
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